Estimation and Comparison of Pro-BNP level in patient with Heart Failure due to COPD and LV dysfunction

  • Dr Bhupendra Kumar Ratre Associate Professor of Medicine,L N Medical College, Bhopal, MP, India.
  • Dr. Narmada Prasad Patel Assistant Professor of Medicine,L N Medical College, Bhopal, MP, India.
  • Dr Varun kumar senior resident, L N Medical College, Bhopal, MP, India.
  • Dr. Umesh Patel Associate Professor of Pediatrics, L N Medical College, Bhopal, MP, India.
  • Dr Roopesh Jain Associate Professor, L N Medical College, Bhopal, MP, India.
Keywords: Congestive heart failure, Left ventricular dysfunction, Pro BNP, Chronic obstructive pulmonary airway disease, Ischemic heart disease


Introduction: Diagnosis of heart failure and chronic obstructive pulmonary disease remains predominantly clinical decision. Many times both the condition may mimic each other and differentiation may be difficult specially in elderly and obese individuals. Pro-BNP is an important marker to distinguish the above conditions. We did a study to estimate and compare the levels of Pro-BNP in patients with heart failure due to COPD and LV dysfunction.

Material and methods: The study subjects were 60 patients of comparable age group admitted in department of medicine and cardiology. Level of pro BNP was assessed using Immune electro chemiluminescence assay (IECMA).

Results: The mean level of pro BNP was significantly raised in patients with heart failure due to LV dysfunction. Left Ventricular Ejection Fraction and levels of Pro BNP were not related.

Conclusion: Pro BNP can serve as a good clinical tool in differentiation of dyspnea arising out of congestive heart failure and chronic obstructive pulmonary airway diseases specially in elderly and obese patients. It is easy to perform and bedside test.


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How to Cite
Dr Bhupendra Kumar Ratre, Dr. Narmada Prasad Patel, Dr Varun kumar, Dr. Umesh Patel, & Dr Roopesh Jain. (2014). Estimation and Comparison of Pro-BNP level in patient with Heart Failure due to COPD and LV dysfunction. Biomedical Review: Journal of Basic and Applied Medical Sciences (JBAMS), 1(1), 3-9. Retrieved from
Original Article