Frequency distribution of blood group with its allelic configuration among the studied population of Delhi NCR region
Introduction: Since the discovery of ABO blood group system by Landsteiner in 1900 and Landsteiner & Wiener in 1940, a voluminous data is available on the frequencies of ABO blood group and also Rh factor for most parts of the world which varies depending on geographical belt including India. In this relation there is no report of occurrence of blood group and Rh factor of the population residing in Delhi-NCR region including Faridabad district. So the present study is undertaken to find out the normal ABO and Rh frequencies among the localites of Delhi-NCR belt along with their allelic frequency and to compare our result with other studies conducted in different parts of India.
Methods: A total of 1178 domicile individuals from Delhi NCR are selected from the BDS students, staffs of the Dental colleges for blood group determination. The ABO and Rh factor are determined immediately after blood collection using the Tile or Slide testing. Allelic frequencies were calculated under the standard assumption of Hardy Weinberg equilibrium. The study was approved by Institutional ethical committee.
Results: It is found that the most common type of blood group is B type followed by O, A and then AB. It is also demonstrated that the observed population of each ABO blood group is in accordance with the expected population as per Hardy-Weinberg’s equilibrium.
Conclusion: The present study shows that the frequency distribution both ABO and Rh blood group among the studied population of Delhi NCR region is in accordance with the north Indian population including Haryana and Delhi and also is in accordance with the expected population as per Hardy-Weinberg’s equilibrium.
2. Landsteiner K, Weiner AS,An agglutinable factor in human blood recognized by immune sera for rhesus blood. Proc.Soc.Exp.Biol.Med., .,1940;43,223-244.
3. Garraty G. Glynn SA. McEntire R. ABO and Rh (D) phenotype frequencies of different racial/ethnic groups in the United States. Transfusion. 2004;44,703-706.
4. Blood Bank.com, racial & Ethnic Distribution of ABO blood types cited 15th March.2005.
5. Reid ME, Lomas –Francis C. The blood group antigen facts. 2nd Edition. 2004. New York; Elsevier Academic Press.
6. Chan KT, 1962, The ABO blood group frequency distribution of Singapore based on a blood donor sample. Sin. Med. J. , 3, 3-15.
7. Das PK, Nair SC, Harris VK, Rose D, Mammen JJ, Bose YN, Sudarsanam A. Distribution of ABO and Rh-D blood groups among blood donors in a tertiary care centre in South India. Trop Doct. 2001 Jan; 31(1):47-8.
8. Mukherjee R, Khatriya GK., 2004, Distribution of blood groups among Brahmins and Rajputs in Himachal Pradesh. Anthropologist., 6(4),293-294.
9. Basak A K & Maji K, Blood group and anemia: Exploring a new relationship. J. Pub. Health & Epi. 2013; 5(1), 43-45,
10. Khaskheli DK, Qureshi AH, Akhund AA, Distribution of ABO and Rh groups in the residents of Sindh. Pak J Health. 1994;31,45-50.
11. Hussain A, Sheikh SA, Haider M, Rasheed T, Malik MR. Frequency of ABO and Rh blood groups in population of Balouchistan (Pakistan). Pak Armed Forces Med. J.2001; 51,22-26.
12. Khattak ID, Khan TM, Khan P, Ali-Shah SM, Khattack ST, Ali A. Frequency of ABO and Rhesus blood groups in district SWAT, Pakistan. J Ayb Med Coll Abbottabad. 2008;20 (4),127-129.
13. Egesie UG, Egesie OJ, Usar I and Johnbull TO. Distribution of ABO, Rhesus blood groups and Hb electrophoresis among the undergraduate students of Nigar delta University, Nigeria, Nijerian J. of Physiological Sciences. 2008; 23(1-2), 5-8.
14. Mahajon B K: Chapter 11, In: Methods in Biostatistics, 6th ed., Japeee Brothers Med. Pub(P) Ltd. Pub, New Delhi, 2006.
15. http: // bioquest. org/ esteem/ esteem_details. php? product _id=209#
16. Agrawal A, Tiwari AK, Mehta N, Bhattacharya P, Wankhede R, Tulsiani S, and Kamath S. Asian J. Transfus Sci.2014; 8(2): 121–125.
17. Sidhu.S and Sidhu LS. ABO blood group frequencies among the Sansis of Punjab. Coll. Anthropol.1980; 4: 55-58.
18. Ahuja.S and Sidhu LS. Distribution of ABO blood groups and some physical traits among the Gujjars of Punjab. Ind.J. Phys. Anthrop. Hum.Genet.1981;7:93-96.
19. Sehgal IK, Chahal SMS, Bansal IJS. Genetic variation in five endogamous groups of Patialadistrict, Punjab. J. Ind. Anthrop. Soc. 1986;21: 63-72.
20. Saini M & Yadav AS. American International Journal of Research in Formal, Applied & Natural Sciences, 2014;6(1), 73-75.
21. Verma U, Singroha R, Malik P. A study to find correlation between dermatoglyphic patterns and abo blood groups, Int J Anat Res 2015;3(3):1293-1297.
22. Bharadwaj A et al., 2004, Pattern of fingerprints in different ABO blood groups. JIAFM,, 26(1):6-9.
23. Mehta AA, Mehta AA, Sonar V. Digital dermatoglyphics in ABO, Rh blood groups. J.I.A.F.M, 2011;33(4):349-351.
24. Yadav B , Raina A, Kumar A, Bansal SK, Dogr TD. Allelic and phenotypic diversity of abo and rhesus (d) blood groups in the medical and dental apprentices of a
university of Haryana, India, Int.Res. J of Nat.& Appl Sci,2014;1(6),57-67.
25. Garg N, Singh DK, Tomar R, Singh B. Phenotype Prevalence of Blood Group Systems (ABO, Rh, Kell) in Voluntary, Healthy Donors-Experience of a Tertiary Care Hospital in Delhi, North India. J Blood Disord Transfus 2015;6: 297. 2-4.
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